Diabetic Cardiomyopathy
Conditions
Interventions
Simple diabetes group:None
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Type 2 diabetes mellitus duration >=5 years; 2. Clinical manifestations of diabetic cardiomyopathy: heart failure, arrhythmia, angina, etc.; 3. Cardiac structural changes or dysfunction diagnosed by cardiac color Doppler ultrasound (meeting the following criteria >=1 item): left ventricular end-diastolic diameter: 35-55 mm in males and 30-50 mm in females, exceeding which indicates left ventricular enlargement; Left atrial anteroposterior diameter: 22-34mm in males and 20-32mm in females, exceeding this indicates left atrial enlargement; End-diastolic ventricular septal thickness: 6-11 mm, exceeding which indicates septal thickening; Left ventricular posterior wall end-diastolic thickness: 6-11 mm, exceeding this indicates left ventricular wall thickening; Left ventricular ejection fraction: LVEF <50%, indicating decreased left ventricular systolic function; Diastolic dysfunction: the ratio of early diastolic peak velocity (peak E) to late diastolic peak velocity (peak A) <1, then diastolic function decreases; 4. If there are other concomitant microangiopathies, such as retinal vascular disease or renal vascular disease, it is more corroborating or supportive of the diagnosis.
Exclusion criteria
Exclusion criteria: 1. Myocardial lesions caused by other diseases; 2. Have type 1 diabetes; 3. Patients with severe liver dysfunction; 4. History of acute and chronic infectious diseases, severe autoimmune diseases or malignant tumors; 5. Suffering from mental illness; 6. Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| General information (gender, age, place of origin, BMI, smoking history, drinking history, hypertension history, liver function, kidney function, blood lipid, etc.);Echocardiographic data; | — |
Countries
China
Contacts
Public ContactYang Jiadan
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed