Biliary tract diseases such as bile duct stones, inflammatory stenosis, malignant tumors, postoperative stenosis or bile leakage
Conditions
Sponsors
ShangHai ChangHai Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Age>18 years old and<=70 years old; 2.BMI 18-30 kg/m^2; 3. ASA levels I-III; 4. The planned anesthesia method is MAC; 5. Patient consent, sign informed consent form
Exclusion criteria
Exclusion criteria: 1. Emergency surgeons; 2. Patients with moderate or above abnormal heart and lung function (such as severe arrhythmia, conduction block, heart failure, hypertrophic cardiomyopathy, dilated cardiomyopathy, pulmonary heart disease, severe valve disease, and respiratory failure); 3. Patients with severe liver and kidney dysfunction (liver enzymes>2 times normal, urea nitrogen>8.2 µ mol/L, creatinine>133 µ mol/L); 4. Use of anticoagulants or coagulation dysfunction (PT>17 s or APTT>47 s); 5. Patients with oral, nasal, and throat infections; 6. Individuals who are allergic to the anesthetics used; 7. Pregnant and lactating women; 8. Patients who are expected to undergo complex or prolonged procedures requiring general anesthesia with endotracheal intubation (pancreatic cyst puncture drainage, EUS-BD, EUS-PD, EUS-GE, etc.); 9. Currently participating in other clinical trials or using other clinical trial drugs within the first 3 months of enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of hypoxemia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of other adverse reactions;Incidence of hypoxemia requiring NPA insertion, incidence of hypoxemia after NPA intervention, incidence of severe hypoxemia, and minimum oxygen saturation;The number and duration of endoscopic pauses caused by anesthesiologist intervention;Incidence of nasal discomfort symptoms;Satisfaction scores of patients, operating physicians and anesthesiologists;Incidence of gastrointestinal adverse reactions; | — |
Countries
China
Contacts
Public ContactLi Bo
ShangHai ChangHai Hospital
Outcome results
None listed