Prognosis of hypokalemia in elderly patients undergoing hip fracture surgery
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Age >=60 years old; (2) Hip surgery: including semi-hip replacement (artificial femoral head replacement), total hip replacement and PFNA; (3) Blood potassium < 3.5mmol/L at first admission;
Exclusion criteria
Exclusion criteria: (1) Serious diseases of cardiovascular system: 1) Have a recent history of myocardial infarction (e.g., within the past 6 months) or are currently in the acute phase of myocardial infarction. 2) Unstable angina pectoris, severe arrhythmias (such as ventricular tachycardia, ventricular fibrillation, etc.), or arrhythmias that require drug or instrument maintenance. 3) Severe valvular heart disease, such as mitral valve, aortic valve stenosis or insufficiency (moderate or above), and accompanied by obvious clinical symptoms. 4) Heart failure, NYHA class ? or ?, or left ventricular ejection fraction (LVEF) <40%. (2) Serious diseases of other systems: 1) Acute or chronic infection, such as sepsis, osteomyelitis, etc., and the infection is not effectively controlled. 2) Liver and kidney failure, such as decompensated cirrhosis, uremia and so on. 3) Severe respiratory diseases, such as acute exacerbation of chronic obstructive pulmonary disease (COPD), respiratory failure, etc. Malignant tumors, especially those that have metastasized or deteriorated rapidly in the near future. (3) Electrolyte and acid-base balance disturbance: 1) Serious electrolyte disorders existed before surgery, including hyperkalemia, hyponatremia, hypernatremia, and hypocalcemia in addition to hypokalemia, and could not be corrected in a short time. 2) Disturbance of acid-base balance, such as severe acidosis or alkalosis. (4) Effects of drugs and special treatments: 1) Preoperative long-term use of drugs that may affect blood potassium level or cardiovascular function, such as potassium diuretics, potassium diuretics, digitalis drugs, etc., and can not be stopped or adjusted dose to not affect the study results. 2) Preoperative treatment that may affect blood potassium levels or cardiovascular function, such as dialysis, hemoperfusion, etc. (5) Incomplete medical records or unreliable data: 1) Medical records are incomplete, lacking critical preoperative, intraoperative or postoperative data. 2) Significant errors or inconsistencies in data recording prevented accurate assessment of preoperative hypokalemia and postoperative cardiovascular events and prognosis. 3) Deaths caused by non-operative factors such as accidents, poisoning or suicide.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mortality at 30 and 180 days after hip surgery in elderly patients; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of postoperative adverse cardiovascular events (atrial fibrillation, ventricular premature, ventricular tachycardia, angina pectoris, myocardial infarction, heart failure, pulmonary embolism, sudden cardiac death);Postoperative complications: postoperative infection (incision infection, lung infection, urinary tract infection, etc.), Deep vein thrombosis and pulmonary embolism;Effect on length of hospital stay; | — |
Countries
China
Contacts
Affiliated Hospital of Southwest Medical University