Radiofrequency/microwave ablation for liver cancer
Conditions
Interventions
The distance between the tumor and the liver envelope is less than 5mm group:Alfentanil + Dexmedetomidine
The distance from liver cancer to liver capsule is >5mm group:Alfentanil + Dexmedetomidine
Sponsors
Zhejiang Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 69 Years
Inclusion criteria
Inclusion criteria: 1. Percutaneous radiofrequency/microwave ablation of liver cancer was proposed 2. Age 18-69 3. Single tumor, tumor size <= 5cm 4. ASA I - III
Exclusion criteria
Exclusion criteria: 1. Patients with severe bradycardia (HR<50 beats/min), sick sinus syndrome, grade 2 or above atrioventricular block without pacemaker implantation 2. Portal hypertension; 3. Severe liver function impairment (Child-Pugh grade C); 4. Renal failure (requiring kidney replacement therapy); 5. The patient refused to participate in this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TCI target control concentration of afentanil; | — |
Secondary
| Measure | Time frame |
|---|---|
| NRS pain score;Cumulative alfentanil dosage;Doctor's anesthesia satisfaction;Adverse event rate;MOAA/S score;Blood pressure;Heart rate;Respiratory rate;Dosage of dexmedetomidine;Patient satisfaction with anesthesia; | — |
Countries
China
Contacts
Public ContactWen Zhang
Zhejiang Cancer Hospital
Outcome results
None listed