Drug-resistant acinetobacter baumannii infection
Conditions
Interventions
Sponsors
Ningxia Medical University General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: ? Patients infected with drug-resistant Acinetobacter baumannii (based on the drug sensitivity test results of our hospital or a hospital above 3A); ? The pathogenic bacteria infected by the patient (Acinetobacter baumannii) should meet one of the following conditions: 1) The pathogen is completely resistant to antibiotics; 2) Pathogen resistance to key antibiotics: resistance to carbapenems or third-generation and above cephalosporin antibiotics. 3) The pathogen is sensitive to the key antibiotics in vitro, but the antibiotic is clinically ineffective or ineffective (the effect is not obvious defined as the clinical effect is not obvious, the condition is not improved or worsened, and the microbial treatment is ineffective (the pathogen cannot be cleared)); 4) The pathogen is limited in the use of critical sensitive antibiotics (such as organ toxicity or patients allergic to this antibiotic); ? At least one lytic phage can be screened (virtual matching is not required); ? It can be administered by spraying, external application, atomizing inhalation, perfusion, local injection or diversion tube through infected foci; ? The subjects and their family members (or guardians) fully read, understand and sign the informed consent.
Exclusion criteria
Exclusion criteria: ? Bacterial infection can be effectively controlled by antibiotic treatment; ? There is no other route of administration except intravenous administration; ? Patients who were determined by the investigators to be unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bacterial culture and identification results; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical Outcomes; | — |
Countries
China
Contacts
Public ContactYang Xiaojun
Ningxia Medical University General Hospital
Outcome results
None listed