infratentorial stroke patients with swallowing disorders.
Conditions
Interventions
Group A:central combine peripheral Intermittent Theta-Burst Stimulation (iTBS)
Group B:central Intermittent Theta-Burst Stimulation (iTBS)
Sponsors
Xi'an Jiaotong University Second Affiliated Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.first-ever brainstem stroke or cerebellar stroke,comply with the '2018 Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 'or the '2014 Chinese Guidelines for the Diagnosis and Treatment of Cerebral Hemorrhage',documented by computed tomography (CT) or magnetic resonance imaging (MRI); 2.duration after stroke >=2weeks and <=12 months,stable condition; 3.18-85 years; 4.swallowing problems after stroke; 5.clear consciousness, stable vital signs and cooperate well with the training; 6.follow the research procedures and cooperate with the implementation of the whole process research; 7.follow the lifestyle precautions during the study; 8.willing to sign the informed consent of this study;
Exclusion criteria
Exclusion criteria: 1.a history of swallowing problems caused by other underlying neurological diseases, such as Parkinson’s disease, dementia, or motor neuron disease; 2.a history of intractable seizure; 3.poor cooperation due to serious aphasia or cognitive disorders; 4.serious dysfunction of liver, kidney, heart and other important organs; 5.implanted pacemaker or metal plate in the skull; 6.inability to undergo a videofluoroscopic swallowing study (VFSS); 7.Individuals with severe visual or hearing impairments; 8.pregnant or lactating women; 9.situation of skull loss; 10.The researcher consider that there are any conditions that may harm the subjects or cause them to be unable to meet or perform the research requirements.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rosenbek penetration-aspiration scale, PAS;video fluoroscopic images for swallowing; | — |
Secondary
| Measure | Time frame |
|---|---|
| Standardized Swallowing Assessment (SSA);Motion Evoked Potential (MEP), Resting Motor Threshold (RMT);functional near-infrared spectroscopy, fNIRS;Safety Assessment;Event-Related Potential, ERP; | — |
Countries
China
Contacts
Public ContactHui Yanping
Xi'an Jiaotong University Second Affiliated Hospital
Outcome results
None listed