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Study of compound chamomile lidocaine gel for perioperative comfort in children with transnasotracheal intubation under general anesthesia

Study of compound chamomile lidocaine gel for perioperative comfort in children with transnasotracheal intubation under general anesthesia

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400093700
Enrollment
Unknown
Registered
2024-12-10
Start date
2024-06-04
Completion date
Unknown
Last updated
2024-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

General anesthesia surgery in children

Interventions

Control group:Apply compound lidocaine cream on the tracheal tube tip and the surface of the cuff
Experimental group:Apply compound chamomile lidocaine gel on the tip of the tracheal catheter and the surface of the cuff

Sponsors

Beijing Children's Hospital affiliated to Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 8 Years

Inclusion criteria

Inclusion criteria: 1. Children with transnasal intubation is required for elective dental pulp treatment under general anesthesia; 2. Age>=3 years, 6 h, no breast milk / formula > 4 h, no clear drinks > 2 h.

Exclusion criteria

Exclusion criteria: 1. epistaxis or transnasal dyspnea; 2. skull base fracture or blood coagulation dysfunction; 3. Intranasal mass, nasal stenosis or nasal septum deviation; 4. Mental development disorders, and autism; 5. Difficult airway is expected; 6. it is expected that anesthetic antagonistic drugs may be applied; 7. History of acute upper respiratory tract infection, history of airway hyperreactivity (e. g., asthma), cough, expectoration, or sore throat in the past 2 weeks; 8. Oral or nasal other indwelling pipes (such as gastric tube); 9. There are contraindications or allergies to test drugs and other anesthetic drugs; 10.To participate in other studies within 30 days.

Design outcomes

Primary

MeasureTime frame
Incidence of epistaxis ;

Secondary

MeasureTime frame
Classification of nosebleed ;Heart rate and mean arterial pressure ;Breath holding, coughing, nasopharyngeal pain, hoarseness and oropharyngeal mucositis;

Countries

China

Contacts

Public ContactLi Lijing

Beijing Children's Hospital affiliated to Capital Medical University

amber1717@163.com+86 189 1055 0202

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026