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Clinical Application Study of Traditional Chinese Medicine Diagnosis and Treatment Techniques for Metabolic Nephropathy

Clinical Application Study of Traditional Chinese Medicine Diagnosis and Treatment Techniques for Metabolic Nephropathy

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400093691
Enrollment
Unknown
Registered
2024-12-10
Start date
2024-03-15
Completion date
Unknown
Last updated
2024-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metabolic nephropathy

Interventions

Experimental group (traditional Chinese medicine):Western basic treatment+oral administration of traditional Chinese medicine
Control group (traditional Chinese medicine):Western medicine basic treatment+placebo
Experimental group (external treatment rehabilitation):Traditional Chinese Medicine External Treatment+Rehabilitation Treatment
Control group (external treatment rehabilitation):Conventional Western Medicine Treatment Western medicinea doctor trained in Western medicine 1. :COPD. Conclusion: TCM combined with
Group B ( 40 cases) was treated with tetramethylpyrazine injection 80 ? 120 mg/ d intravenous drip besides conventional therapy
dict.cnki.net 4. ,SAP. Treatment effectiveness of integrated TCM-WM is better than conventional therapy of west medicine. Now, TCM is become one of important complementary therapies of

Sponsors

Ningbo Municipal Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Western medicine diagnosis meets the diagnostic criteria of diabetes nephropathy/uric acid nephropathy, and GFR >= 30ml/min/1.73m^2; 2. Traditional Chinese medicine syndrome differentiation is consistent with spleen and kidney deficiency, turbidity and stasis resistance syndrome; 3. Age between 18-75 years old; 4. Accompanied by hypertension (with medication to control blood pressure <= 130/80mmHg) or without hypertension; 5. Have been taking Irbesartan tablets continuously for 2 weeks or more; 6. The subject agrees and signs an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients with severe diseases of important organs, such as moderate to severe liver dysfunction (transaminase levels three times higher than normal), malignant tumors, severe anemia (HB less than 60g/L), and those who have undergone cardiovascular and cerebrovascular stenting in the past three months; 2. Those who are currently taking hormones or immunosuppressants; 3. Individuals who are allergic to known components of the investigational drug or have a severe allergic constitution; 4. Pregnant or lactating women; 5. Existence of neurological and psychiatric disorders; 6. Participated in other clinical trials within the first 3 months of screening, and also participated in other trial projects during this period; 7. Other situations where the researcher judges poor compliance or deems it unsuitable to participate in the trial; 8. After adjusting the antihypertensive medication, the blood pressure is greater than 180/90mmHg or less than 90/60mmHg; Or after clinical treatment, blood potassium levels may exceed 5.5mmol/L.

Design outcomes

Primary

MeasureTime frame
renal function;Urinary protein/creatinine;Rehabilitation Rating Scale (QOL, MMT, ROM, FIM);

Secondary

MeasureTime frame
glomerular filtration rate;blood electrolyte;liver function;blood fat;blood sugar;Blood routine;Urinalysis;Urinary NAG enzyme;Blood Metabolomics;Urinary Metabolomics;

Countries

China

Contacts

Public ContactGuanghui Zhong

Ningbo Municipal Hospital of Traditional Chinese Medicine

zgh20040712@126.com+86 139 5780 5920

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026