schizophrenia
Conditions
Interventions
Continuous intervention group:Use 40IU of oxytocin daily for 7 consecutive days
Interval intervention group:Use 40IU oxytocin on Day 1, Day 3, Day 5, and Day 7
placebo group:Use 0.9% saline solution continuously for 7 days
Sponsors
Zhenjiang Mental Health Center
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Gender: Unrestricted (2) Age: 18-65 years old (3) DSM-V structured clinical interviews diagnosed patients with schizophrenia for at least 1 year and hospitalized for at least 8 weeks. (4) The type and dosage of antipsychotic medication should be stable for at least 4 weeks. (5) PANSS score = 55; PANSS hallucination and fantasy scores do not exceed a moderate to severe rating (= 4).
Exclusion criteria
Exclusion criteria: (1) Intellectual disability (IQ equal to or below 70). (2) Have a history of alcohol or substance addiction in the past year. (3) Hypertension, heart problems, or any major non mental illness or hospitalization. (4) Calgary Depression Scale (score greater than 10).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Positive and Negative Syndrome Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Wechsler Intelligence Scale;Calgary Depression Scale;Positive and Negative Emotion Scale; | — |
Countries
China
Contacts
Public ContactJingJing Sun
Zhenjiang Mental Health Center
Outcome results
None listed