FindTrial
Sign In

Study on differences in the efficacy of repetitive transcranial magnetic stimulation in the treatment of neuropathic pain after spinal cord injury

Study on differences in the efficacy of repetitive transcranial magnetic stimulation in the treatment of neuropathic pain after spinal cord injury

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400093680
Enrollment
Unknown
Registered
2024-12-10
Start date
2024-12-12
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

spinal cord injury

Interventions

active rTMS:A figure-of-eight coil was used to target the left primary motor cortex (M1). Treatment parameters: frequency 10 Hz, 80% resting motor threshold, 1.2s on, 3s off, total pulse number 1200
sham rTMS:A sham stimulus with no output was given an acoustic cue at the same frequency as the true stimulus
Health Control:None

Sponsors

The First Affiliated Hospital of the Air Force Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patient: 1. Aged from 18 to 70 years old; 2. Right handedness (Edinburgh Handedness Inventory); 3. SCI patients with disease duration <=1 year; 4. Meet the diagnostic criteria for NP; 5. Sign informed consent. Health control: 1. Aged from 18 to 70 years old; 2. Sign informed consent.

Exclusion criteria

Exclusion criteria: Patient: 1. The presence of chronic non-neuropathic pain such as skeletal muscle pain and visceral pain; 2. the presence of conductive, ferromagnetic or other magnetic sensitive metal in the head and neck, or the presence of a cardiac pacemaker; 3. History of seizures or family history; 4. Accompanied by blood system disease/serious medical disease/mental disease/dementia/cognitive disorder/consciousness disorder; 5. Received rTMS treatment within 2 weeks; 6. The woman is pregnant. Health control: The same as that of the patient, and the first item is changed to "Any pain exists".

Design outcomes

Primary

MeasureTime frame
pain;—

Secondary

MeasureTime frame
emotion;motor function;activities of daily living;sensory function;paired-pulse transcranial magnetic stimulation (ppTMS);high density electroencephalogram (hdEEG) indicators;TMS-EEG indicators;motor evoked potential (MEP);sensory evoked potential (SEP);brain-derived neurotrophic factor (BDNF) polymorphism;resting motor threshold (RMT);—

Countries

China

Contacts

Public ContactYuan Hua

The First Affiliated Hospital of the Air Force Medical University

yuanhua@fmmu.edu.cn+86 29 8477 5439

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026