Obesity and insulin resistance
Conditions
Interventions
Normal control group:None
Sponsors
Chongqing Dazu District People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1.100 cases of type 2 diabetes group: patients with type 2 diabetes mellitus whose blood glucose is not controlled by diet and exercise. Type 2 diabetes mellitus was diagnosed according to the 1999 WHO criteria; 2.100 cases of simple obesity group: BMI >= 28kg/m^2; 3. equal number of normal control group. All subjects need to meet the age of 18-75 years old, male or female; no serious diseases of various systems; able to understand and willing to strictly comply with the clinical trial protocol to complete the trial, and voluntarily sign the informed consent.
Exclusion criteria
Exclusion criteria: Exclusion criteria (fulfilment of one of the following precludes enrolment): 1. the patient is allergic to the drugs involved in the study; 2. use of any of the following drugs or treatments prior to randomisation: 1) Growth hormone within 6 months; 2) History of substance abuse within 6 months; 3) Use of any glucose-lowering medication within 2 months; 4) Participation in a clinical trial of any drug or medical device within 2 months; 5) Use of more than 7 days of corticosteroid therapy within 2 months; 6) Use of medication with weight control effects (e.g., sibutramine, rimonabant, orlistat) or any procedure that can cause weight change within 2 months; 7) Use of any kind of medication that could have an impact on the safety of the treatment and the accuracy of the data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Obeisty;Insulin resistance; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammatory factors; | — |
Countries
China
Contacts
Public ContactYanping Wang
Chongqing Dazu District People's Hospital
Outcome results
None listed