Myopia and myopic astigmatism
Conditions
Interventions
Customed FS-LASIK group(wavelight plus):Customed FS-LASIK(wavelight plus) was performed based on the principle of whole eye aberration tracing.
SMILE group:The surgery of femtosecond laser small incision lenticule extraction (SMILE, Visumax500) was performed.
Sponsors
Beijing Tongren Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1) Myopic patients aged 18-40 years; 2) Preoperative degree of myopic sphere from -0.5D to -8D, spherical equivalent(SE)<=-11D, myopic astigmatism <=-3.0D, in line with the treatment degree of wavelight plus or SMILE ; 3)The preoperative best corrected visual acuity(BCVA) is 20/20; 4) Stable refraction (SE growth does not exceed 0.5D 1 year before surgery), the difference of manifest refractive spherical equivalent(MRSE) and sightmap aberration detector does not exceed 0.5D; 5) No eye surgery history, being able to complete the follow-up; The number of patients with low, moderate and high myopia was roughly the same in both groups.
Exclusion criteria
Exclusion criteria: 1) Central corneal thickness <480µm; 2) Postoperative predictive residual stromal bed(RSB) thickness <280µm; 3) Clinically significant corneal abnormalities include corneal degeneration, keratoconus, corneal scar at optic axis, anterior basement membrane dystrophy, etc; 4) Moderate to severe dry eye; 5) Retinal diseases or optic neuropathy that affect vision; 6) Cataract; 7) Glaucoma; 8) Pregnancy or lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| UDVA of 3 months after surgery (uncorrected distance visual acuity); | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean uncorrected distance visual acuity(UDVA);Mean corrected distance visual acuity(CDVA);Manifest refractive spherical equivalent(MRSE);HOA(Total higher order aberration, coma, spherical aberration);Percentage of UDVA more than 1 line,2 lines or over 2 lines before the surgery;Percentage of UDVA reaches 20/10,20/12.5,20/16,20/20,20/25,and20/32;Percentage of MRSE in range of ±0.25D,±0.50D,±075D,and±1.0D;Percentage of residual astigmatism in range of -0.25D,-0.50D,-0.75D,and-1.0D; | — |
Countries
China
Contacts
Public ContactZhai Changbin
Beijing Tongren Hospital, Capital Medical University
Outcome results
None listed