Biliary and pancreatic diseases
Conditions
Interventions
Dexmedetomidine group :Patients in the Dex group will receive four sprays of dexmedetomidine nasal spray, 100µg in totle, at 15 min before induction in 2 min
Normal saline group :Patients in the NS group will receive four sprays of 0.9% saline nasal spray at 15 min before induction in 2 min
Sponsors
The First Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. 18 - 70 years old; 2. ASA (American Society of Anesthesiologists) physical status classification grade I - III; 3. Patients scheduled for elective endoscopic retrograde cholangiopancreatography (ERCP).
Exclusion criteria
Exclusion criteria: 1. Patients with allergies or contraindications to the study medications; 2. Patients with severe bradycardia (heart rate < 50 beats per minute), second-degree or higher atrioventricular block without a pacemaker implanted, sick sinus syndrome, or severe cardiopulmonary insufficiency; 3. Patients who have been using sedatives or opioid drugs for a long time; 4. Those who are difficult to communicate with or who refuse to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total dosage of propofol; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of hypotension and hypoxemia;Fatigue score; | — |
Countries
China
Contacts
Public ContactPeng Ke
Department of Anesthesiology, The First Affiliated Hospital of Soochow University
Outcome results
None listed