Intracranial atherosclerotic stenosis
Conditions
Interventions
Medical-therapy:None
Nimodipine:None
Butylphthalide group:None
EVT:None
Sponsors
Jiangjin Central Hospital of Chongqing
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.Age 12-18 years old; 2.Intracranial atherosclerotic stenosis (> 50% or occlusion) of the anterior circulation confirmed by MRA or CTA; 3.stroke or TIA; 4.mRS <=1;
Exclusion criteria
Exclusion criteria: 1.Extracranial cervical vessel stenosis > 50%; 2.Clinically confirmed intracranial artery stenosis related to non-atherosclerotic causes, such as dissection, vasculitis, moyamoya disease, embolism, immune system diseases, etc; 3.Other stroke etiological subtypes confirmed by clinical diagnosis, such as cerebral hemorrhage, subarachnoid hemorrhage, cardiogenic embolism, etc; 4.Clinically confirmed neurodegenerative diseases, such as Alzheimer's disease, dementia with Lewy bodies, frontotemporal lobar degeneration, Parkinson's disease, etc; 5.Other comorbidities that may affect the outcome and follow-up, such as traumatic brain injury, multiple sclerosis, encephalitis, cancer, poisoning, syphilis, and serious heart, lung, liver, kidney, and endocrine diseases; 6.Informed consent was refused;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Near-infrared functional brain imaging data;MMSE/MoCA; | — |
Secondary
| Measure | Time frame |
|---|---|
| mRS Score; | — |
Countries
China
Contacts
Public ContactZuowen Zhang
Jiangjin Central Hospital of Chongqing
Outcome results
None listed