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SLC25A1 regulates KDM4 activity to promote DNA damage repair leading to radioresistance in non-small cell lung cancer

SLC25A1 regulates KDM4 activity to promote DNA damage repair leading to radioresistance in non-small cell lung cancer

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400093627
Enrollment
Unknown
Registered
2024-12-09
Start date
2025-01-01
Completion date
Unknown
Last updated
2024-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

non small cell lung cancer

Interventions

Lung squamous cell caicinama group:None
Lung adenocarcinoma group:None
large-cell lung cancer:None

Sponsors

Chongqing University Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: Age between 18-85 years, no history of tumor, definite diagnosis of non-small cell lung cancer, and no preoperative radiotherapy or targeted therapy.

Exclusion criteria

Exclusion criteria: Patients with other malignant tumors; women during pregnancy; patients with severe organ dysfunction; patients with acute complications.

Design outcomes

Primary

MeasureTime frame
Target mRNA transcription levels;Target protein expression level and histone methylation status;Spatial distribution of target proteins;

Countries

China

Contacts

Public ContactKexu Xiang

Chongqing University Cancer Hospital

xkx183@outlook.com+86 191 2285 5008

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026