Sepsis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Randomly enrolled patients admitted to the intensive care unit of the anesthesia department and the intensive care medicine department of Nanjing Drum tower Hospital. Individuals who have entered for less than 24 hours, are over 18 years old, and weigh over 20 kg. Informed consent was obtained from the participating volunteers, patients or their representatives.
Exclusion criteria
Exclusion criteria: 1) Refusing to participate in the experiment and not signing the informed consent form; 2) The patient is in a state of hemorrhagic shock or severe anemia; 3) Severe hematopoietic system diseases before onset; 4) Serious history of mental illness, etc; 5) Quitting the researcher midway.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neutrophil-derived extracellular vesicles;Neutrophil extracellular traps; | — |
Secondary
| Measure | Time frame |
|---|---|
| Organ dysfunction index;Mortality at 28 Days;Mechanical ventilation time and CRRT time;Patient ICU and total length of hospital stay;Inflammatory markers;General vital signs and laboratory indicators of patients;Incidence of complications in cured patients; | — |
Countries
China
Contacts
Nanjing Drum Tower Hospital