Soft tissue deficiency
Conditions
Interventions
Experimental group of keratinized gingiva augmentation:keratinized gingiva augmentation with gelatin-polycaprolactone gingival repair film
Control group of keratinized gingiva augmentation:None, routine implant surgery is performed
Experimental group of alveolar ridge preservation:Alveolar ridge preservation with gelatin-polycaprolactone gingival repair film
Control group of alveolar ridge preservation:None, regular sites are saved
Experimental group of peri-implant soft tissue augment:Peri-implant soft tissue augment with gelatin-polycaprolactone gingival repair film
Sponsors
Zhejiang Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Experiment 1: (1) Patients aged >=18 years old, healthy in the past, without complaints of systemic diseases; (2) insufficient keratinized gingiva; (3) no acute periodontal inflammation; (4) no infection of soft tissue wound; (5) Patients had good compliance; (6) agree to participate in this clinical trial and sign the informed consent. Experiment 2: 1) 18 years old = 3mm; 4) no acute periodontal inflammation; 5) those with good compliance and can cooperate to complete the whole clinical trial; 6) Able to understand the purpose of the trial, voluntarily participate and sign informed consent. Experiment 3: 1) 18 years old <= age <=70 years old, regardless of gender; 2) patients with labial and buccal gingival depression requiring soft tissue augmentation in the second stage of implant placement; 3) no acute periodontal inflammation; 4) those with good compliance and can cooperate to complete the whole clinical trial; 5) Able to understand the purpose of the trial, voluntarily participate and sign informed consent.
Exclusion criteria
Exclusion criteria: (1) Acute infection of affected teeth or adjacent teeth and soft tissues; (2) female patients during pregnancy or lactation; (3) taking drugs affecting platelet or bone regeneration within 3 months; (4) patients with a history of head and neck radiotherapy and uncontrolled systemic diseases; (5) heavy smokers, smoking more than 10 cigarettes/day; (6) Gelatin allergy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Keratinized gingival width at 6 months after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in alveolar bone height and width at 6 months after surgery; | — |
Countries
China
Contacts
Public ContactFan Yang
Zhejiang Provincial People's Hospital
Outcome results
None listed