Perioperative venous thromboembolic disease during lumbar spine surgery
Conditions
Interventions
No Drug Prevention Group (blank control group):Basic Prevention+physical prevention+no drug prevention
Drug Prevention Group (aspirin group):Basic Prevention + Physical Prevention + Aspirin 100 mg/d x 14 days
Drug Prevention Group (Intervention Group 2: Rivaroxaban Group):Basic Prevention + Physical Prevention + rivaroxaban 10 mg/d x 14 days
Sponsors
the Seventh Affiliated Hospital, Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. 2024 10- 2026 09 Lumbar admitted. 2. Aged 18 to 80;
Exclusion criteria
Exclusion criteria: 1. Age under 18 or over 80; 2. Patients receiving preoperative anticoagulation therapy and patients with medical contraindications to both study drugs; 3. Except for patients with cancer 4. Except for patients for whom no prophylaxis is recommended. 5. Except for patients with an existing bleeding event. 6. Postoperative use of a variety of thromboprophylaxis in patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of VTE within 30 days after operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cumulative incidence of VTE within 90 days;Bleeding events within 30 days and 90 days after discharge;Major risk factors for VTE; | — |
Countries
China
Contacts
Public ContactFuxin Wei
The Seventh Affiliated Hospital of Sun Yat sen University (Shenzhen)
Outcome results
None listed