Diabetic Retinopathy
Conditions
Interventions
anti-VEGF group:Intravitreal injection of Conbercept
PRP group:pan retinal photocoagulation
Sponsors
Eye & ENT hospital of Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Be able to follow the experimental protocol and prescribed procedures, and sign informed consent forms; 2.According to conventional ophthalmic examinations such as ultra wide angle ss OCTA and ultra wide angle fundus photography, patients with high-risk proliferative diabetes retinopathy were diagnosed (referring to relevant literature, high-risk PDR was defined as: small pieces of pre retinal hemorrhage; or ultra wide angle ss OCTA saw the presence of neovascularization in the optic disc or retina at any image limit; and there was no vitreous hemorrhage, retinal detachment and neovascular glaucoma); 3.Individuals who voluntarily receive PRP treatment or anti VEGF treatment; 4.Acceptable for long-term regular check ups in this hospital; 5.Age 18 years and above.
Exclusion criteria
Exclusion criteria: 1.Patients with severe diabetes, hypertension and other basic diseases with poor control; 2.Patients who have undergone PRP or vitrectomy surgery; 3.Individuals who have undergone cataract surgery or anti VEGF treatment within the past 6 months; 4.Patients with active eye infections, uveitis, glaucoma, and other comorbidities.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Best corrected visual acuity,BCVA;Area of no perfusion zone;Area of angiogenesis; | — |
Secondary
| Measure | Time frame |
|---|---|
| intraocular pressure;Macular fovea thickness;Number of patients with disease progression; | — |
Countries
China
Contacts
Public ContactZou Chen
Eye & ENT hospital of Fudan University
Outcome results
None listed