Healthy elderly
Conditions
Interventions
Transcranial direct current stimulation group:Scheme 1: Set the stimulation intensity of the transcranial direct current stimulation device to 1mA and conduct continuous treatment for 10 minutes.
Sche
Transcranial magnetic stimulation group:Scheme 1:
Set the transcranial magnetic stimulation device to a frequency of 10 Hz, RMT 90%, 1200 pulses, 20 minutes, stimulate for 1 second and rest for 9 seco
Sponsors
Beijing Rehabilitation Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age between 40 and 80 years old; 2. No severe neurological diseases, such as severe cerebral infarction (modified Rankin scale score >= 3 points), sequelae of cerebral hemorrhage affecting limb motor function (lower limb motor function evaluated by Fugl-Meyer = 4 stages), etc; 3. No severe cardiovascular diseases, such as severe heart failure (New York Heart Association cardiac function classification grade III-IV), unstable angina pectoris (Canadian Cardiovascular Society angina pectoris classification grade III-IV), etc; 4. No musculoskeletal system diseases, such as unhealed fractures, severe joint deformities (joint range of motion reduction > 50%), etc; 5. No open wounds, skin infections, rashes, etc. on the limbs that affect the adhesion of electrode patches and the implementation of electrical stimulation; 6. Able to understand and willing to abide by all procedures stipulated in the protocol; 7. The subject himself or his legal representative signs the Informed Consent Form.
Exclusion criteria
Exclusion criteria: 1. Unable to understand words or there are any factors that may hinder the completion of neuropsychological assessment; 2. Have a history of alcohol or drug abuse; 3. Be using drugs that may affect this study, including sedatives, anti-anxiety drugs, hypnotics, nootropic drugs and cholinergic drugs, etc; 4. There is a sharp change in body function within 30 days; 5. Currently being treated with force, sound, light, magnetism, electricity and cannot stop; 6. Have a cochlear implant, a pacemaker, an implantable device (i.e., deep brain stimulation, or metal in the brain).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Average power of alpha wave;Average power of theta waves;Average power of beta waves;?-? phase-amplitude coupling value;Task-related ERP; | — |
Secondary
| Measure | Time frame |
|---|---|
| comfort rating;fatigue score;tolerance score;blood pressure;Heart rate variability;respiratory rate;Muscle oxygen saturation;blood oxygenation index;Maximum voluntary contraction force value of muscle;Mean difference of electromyogram amplitude;Muscle hardness value;muscle tone magnitude;Peak difference of electromyogram amplitude;muscle power; | — |
Countries
China
Contacts
Public ContactQie Shuyan
Beijing Rehabilitation Hospital, Capital Medical University
Outcome results
None listed