Effect of blood flow restriction combined with low-intensity resistance training on upper limb function and daily activity ability in patients with high spinal cord injury

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400093542

Enrollment

Unknown

Registered

2024-12-06

Start date

2023-04-05

Completion date

Unknown

Last updated

2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

spinal cord injury

Interventions

LIRT:Routine upper limb resistance training, and control group patients undergo routine low-intensity resistance training of both upper limbs. The patient held their hands on the Mortor Med movable up

BFR+LIRT:Upper limb resistance training in flow restriction conditions, and patients in the trial group require low-intensity resistance training in both upper limbs in the BFR condition. After the pr

Eligibility

Sex/Gender

All

Age

25 Years to 55 Years

Inclusion criteria

Inclusion criteria: (1) Aged between 25 and 55; (2) A diagnosis of C5-C7 spinal cord injury with a course of more than 6 months; (3) Muscle strength of key muscles of both upper limbs = 3; (4) Be able to maintain a wheelchair for at least 20 minutes; (5) MMSE score =24, can cooperate with researchers for inspection; (6) The patient was right-handed in daily life; (7) Voluntarily participate in the 6-week intervention and 4-week follow-up, and sign the informed consent.

Exclusion criteria

Exclusion criteria: (1) Abnormal acute blood pressure response after exercise was tested before intervention, that is, systolic blood pressure rose >30mmHg; Diastolic blood pressure Liter >20mmHg (safety index); (2) There is a blood circulation disorder, coagulation dysfunction; (3) Patients with diabetes, hypertension, and history of varicose veins and deep vein thrombosis (3 years); (4) Upper extremity improved Ashworth grade 2 or above, and the upper extremity joint motion was severely limited; (5) heart, lung, kidney and other important organs are not fully functional, and the body is extremely weak; (6) There is active infection, cancer, pregnancy or intervention intolerance; (7) autonomic nerve reflex disorders or abnormalities.

Design outcomes

Primary

Measure	Time frame
Spinal Cord Independence Measure-?,SCIM-?;Muscle Thickness;	—

Secondary

Measure	Time frame
muscle strength;Circumference;Capabilities of Upper Extremity Questionnaire,CUE-Q;Spinal Cord Injury of Dysfunction Quality of Life Rating Scale,SCIDOLRS;Spinal Cord Injury of Dysfunction Quality of Life Rating Scale;	—

Countries

China

Contacts

Public ContactFubiao Huang

China Rehabilitation Research Center

huangfubiao123@126.com+86 135 2271 8130

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026