Colorectal cancer
Conditions
Interventions
Group A:Driving pressure titration PEEP increment method
Group B:Driving pressure titration PEEP decrement method
Group C:Traditional protective ventilation strategies((PEEP:5 cmH2O))
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
60 Years to 100 Years
Inclusion criteria
Inclusion criteria: Frail patients scheduled for laparoscopic colorectal cancer surgery, aged >= 60 years, regardless of gender, ASA body mass index II or III, BMI <30 kg/m^2, no history of mental illness, and expected surgery time of more than 2 hours.
Exclusion criteria
Exclusion criteria: Refusal to sign the informed consent form; severe chronic obstructive pulmonary disease (GOLD lung function grade 3-4); mental illness or long-term use of psychiatric drugs; central nervous system diseases with impaired respiratory function.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Atelectasis;Respiratory compliance;Oxygenation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamics;Measure the patient's diaphragm thickness, transverse chest diameter and anteroposterior diameter and calculate the ratio;The occurrence of PPCs was followed up 7 days after surgery;Postoperative oxygen use time;Length of hospital stay ;Systemic immune inflammatory index within 24 hours after surgery; | — |
Countries
China
Contacts
Public ContactZhentao Sun
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed