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Clinical efficacy and safety evaluation of dissolving acupoint microneedles with tanshinone IIA in the treatment of chronic stable angina

Clinical efficacy and safety evaluation of dissolving acupoint microneedles with tanshinone IIA in the treatment of chronic stable angina

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400093487
Enrollment
Unknown
Registered
2024-12-05
Start date
2024-06-06
Completion date
Unknown
Last updated
2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic stable angina

Interventions

Treatment group:High frequency acupoints Neiguan (PC6 bilateral), Danzhong(RN17),Xinshu (BL15 bilateral), and Zusanli (ST36 bilateral)) were used for administration, and the positioning was carrie
A course of treatment lasts for 4 weeks, with a total of 2 courses and 24 treatments.
Control group:High frequency acupoints Neiguan (PC6 bilateral), Danzhong(RN17),Xinshu (BL15 bilateral), and Zusanli (ST36 bilateral)) were used for administration, and the positioning was carried out

Sponsors

the First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria of ACC/AHA coronary heart disease stable angina pectoris (CCS grade I.-IV. can be included) 2. 35 years old< = age< = 80 years old, both men and women; 3. Have not taken psychotropic drugs in the past 3 months; 4. No serious breakage, rash, etc., no history of adhesive tape allergy in the treatment of local skin; 5. Those who have a certain level of knowledge and culture (because it is necessary to complete the angina diary and fill in the relevant questionnaires), have good compliance, are willing to cooperate with the research, and sign the informed consent form; Note: Only patients who meet the above 5 criteria can be included in this study.

Exclusion criteria

Exclusion criteria: 1. Pregnant and lactating women, and those who have childbearing requirements in the past six months; 2. Patients with hematopoietic system diseases, heart, liver, spleen, lung, kidney and other serious primary diseases and high-sensitivity constitution; 3. Patients with acute coronary syndrome (including acute myocardial infarction, unstable angina), severe arrhythmia, atrial fibrillation, primary cardiomyopathy, valvular heart disease; 4. Those who have received acupuncture treatment for cardiovascular disease in the past 3 months and are participating in other clinical trials. Note: Subjects who meet any of the above criteria are not allowed to be included.

Design outcomes

Primary

MeasureTime frame
Anginal Frequency;

Secondary

MeasureTime frame
24-hour dynamic electrocardiogram ST-T segment change results; Score of VAS scale;Score of Seattle Angina Questionnaire;Dosage of Nitroglycerin Tablets;6-minute walking distance;

Countries

China

Contacts

Public ContactCui Jin;Xue Kaiyang

the First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine

516260179@qq.com+86 139 8502 6278

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026