Shock
Conditions
Interventions
Standard anti-shock therapy group:Normal saline 500 mL was given for rapid rehydration and norepinephrine intravenous pumping was given to achieve a target systolic blood pressure of 120 mmHg
LIPU stimulation + standard anti-shock therapy group:Low-intensity pulsed ultrasound stimulation of the neck was given, and 500 mL of normal saline fluid was given at the same time, and norepinephrine
Sponsors
Tianjin Medical University General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients with traumatic hypovolemic shock aged >=18 years admitted to ICU and NICU; 2. Patients with invasive arterial blood pressure monitoring; 3. Patients with systolic blood pressure <=100mmHg and urine volume <0.5ml/kg/h; 4. Patients with mild or moderate traumatic hypovolemic shock with 1<=SI (shock index) <=2; 5. Patients with complete case information. 6. The subjects understood and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with unstable conditions and estimated survival time of less than 24 hours; 2. Patients with non-traumatic shock; 3. Perioperative patients; 4. Patients in pregnancy; 5. Patients with carotid artery plaques who are at risk of LIPU stimulation; 6. Patients who refuse or are unwilling to cooperate with this subject; 7. Patients who are considered unsuitable to join the study by the researchers. The general condition of the patient is extremely poor, such as: multiple organ failure; severe cardiopulmonary complications, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to reach target blood pressure after LIPU stimulation;Norepinephrine dosage to achieve target after LIPU stimulation; | — |
Secondary
| Measure | Time frame |
|---|---|
| mRS scores of patients after 1 month and 3 months; | — |
Countries
China
Contacts
Public ContactRongcai Jiang; Chenrui Wu; Yu Tian
Tianjin Medical University General Hospital
Outcome results
None listed