Liver Disease
Conditions
Interventions
QLB-LSAL group:The patient is positioned in a lateral decubitus position. A low-frequency convex array probe is used to locate the T12-L1 paravertebral space and scan the quadratus lumborum muscle al
TAPB group:Bilateral Transversus Abdominis Plane (TAP) block in the transverse plane group: Select the subcostal approach for block. The patient is in a supine position. Using a low-frequency probe, l
Sponsors
The second hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Age: 18-75 years old, 2. ASA classification I-III, 3. Patients scheduled for laparoscopic liver surgery.
Exclusion criteria
Exclusion criteria: 1.BMI < 18 kg/m2 or BMI = 30 kg/m2, 2. Chronic addiction to opioids or long-term alcohol abuse, 3. Allergy to local anesthetics, 4. Contraindications to nerve blocks, such as local infection, abnormal coagulation function, and anatomical abnormalities, 5. Severe cardiovascular and hematologic diseases, 6. Preoperative cognitive dysfunction and inability to cooperate with pain assessment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| morphine equivalent consumption at 24 hours postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Numeric Rating Scale (NRS) scores for both groups at rest and on movement at 2, 4, 6, 12, 24, and 48 hours post-surgery;Postoperative recovery -15 score administered one day before surgery and one and three days after surgery.;Number of cases of rescue analgesia given 48 hours after surgery;he number of invalid bolus attempts for Patient-Controlled Intravenous Analgesia (PCIA) within 48 hours after surgery;analgesia satisfaction scores related to analgesia after 48 hours;Incidence of postoperative nausea and vomiting;Time to get out of bed after surgery for the first time;length of postoperative hospital stay;morphine equivalent consumption at 48 and 72 hours postoperatively;Postoperative complications: dizziness, headache, nausea and vomiting, drowsiness, respiratory depression, urinary retention, and complications related to nerve block (local anesthetic toxicity, puncture site infection, lower limb weakness or paralysis, visceral damage, etc.); | — |
Countries
China
Contacts
Public ContactLingling Jiang
The second hospital of Anhui Medical University
Outcome results
None listed