Lung tumor
Conditions
Interventions
Interventional group: thoracic paravertebral blockade with Lipome bupivacaine
Control group: thoracic paravertebral blockade with Ropivacaine
Sponsors
the First Affiliated Hospital of Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) Patients aged 18-70 years, scheduled for elective Video-assisted thoracoscopic surgery for lung cancer . 2) Preoperative blood routine, biochemical, and electrocardiogram examinations have been completed without obvious abnormal. 3) Patients have no history of drug allergy, and respiratory, circulatory, liver, renal or endocrine disorders. 4) American Society of Anesthesiologists (ASA) classifications ?-?. 5) Body Mass Index(BMI)18 to 28 kg/m^2 6) Can accurately understand the NRS scoring criteria and the usage of PCIA 7) Signed the consents voluntarily
Exclusion criteria
Exclusion criteria: 1) Patients who are allergic to liposomal bupivacaine and any anesthesia related drugs; 2) Severe dysfunction of the heart, lungs, liver, and kidneys 3) History of chronic respiratory diseases (such as chronic obstructive pulmonary disease ,Emphysema or asthma), respiratory and pulmonary infections within 2 weeks before surgery; 4) Patients transitioning to open chest surgery during surgery; 5) Patients with other acute and chronic pain disorders; 6) Suffering from neurological and psychiatric disorders such as epilepsy and cognitive dysfunction; 7) patients and their family members refused to participate in this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Numerical Rating Scale pain scores at rest and on movement;Consumption of hydromorphone recorded on patient-controlled analgesia(PCA) pump;Ratio of doses given and doses attempted; Frequency of rescue analgesia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of adverse effects;The incidence and severity of pain after discharge o; | — |
Countries
China
Contacts
Public ContactXiaoxia An
The First Affiliated Hospital, Zhejiang University School of Medicine
Outcome results
None listed