sepsis-induced hypotension and septic shock
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age 18 years or older; 2.Patients with sepsis-induced hypotension or septic shock who require fluid resuscitation; 3.An indwelling central venous catheter placed via the internal jugular or subclavian vein; 4. A predicted ICU stay longer than 48h.
Exclusion criteria
Exclusion criteria: 1.History of renovascular stenosis, liver cirrhosis or portal hypertension; 2.Patients receiving mechanical circulatory support such as lABP, ECMO; 3.Patients with an infusion of >2L of IV fluid before enrollment; 4.Pericardial effusion,pulmonary embolism or pulmonary hypertension from all causes; 5.Patients who cannot undergo ultrasound examination due to factors such as positioning, skin lesions; 6.Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VExUS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cumulative fluid balance ;Duration of mechanical ventilation;Length of ICU stay;Hospital mortality; | — |
Countries
China
Contacts
Affiliated Hospital of Weifang Medical University