obsessive-compulsive disorder
Conditions
Interventions
experimental group:dTMS+medicine
control group:Sham stimulation+medicine
Sponsors
Second Xiangya Hospital of CSU
Eligibility
Sex/Gender
All
Age
16 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Between the ages of 16 and 50, right-handed; 2. Meet the diagnostic criteria of obsessive-compulsive disorder, meet YBOCS >=6 points; 3. Patients who regularly took sertraline for 2 months or more and did not respond to drug therapy; 4. Have self-awareness, clear understanding of the content of the study, can complete the entire experiment, and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1.The patient has a present or previous history of any of the following conditions: schizophrenia or other psychotic disorder, dementia or any other neurodegenerative disease, alcohol or substance dependence, any mental illness caused by physical illness or drugs; 2.There are contraindications for transcranial magnetic stimulation, such as the presence of metal or electronic instruments in the skull, brain tissue disease, epilepsy, and electroconvulsive therapy in the past 4 weeks. 3.The patient has claustrophobia; 4.Patients are unable to read and understand patient information forms and informed consent forms or patient self-assessment questionnaires; 5.The patient has serious suicidal tendencies; 6.The patient is participating in other clinical trials;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| OCD symptom;fMRI;fNIRs; | — |
Countries
China
Contacts
Public ContactWeihui Li
Second Xiangya Hospital of CSU
Outcome results
None listed