Postoperative cognitive dysfunction
Conditions
Interventions
2:Deep anesthesia
1:Superficial anesthesia
Sponsors
Zhangzhou Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 85 Years
Inclusion criteria
Inclusion criteria: Men or women who have undergone elective orthopedic surgery in Zhangzhou Hospital, Fujian Province; Over 60 years old; American Association of Anesthesiologists (ASA) 1 or 2; Informed consent of patients and their families; Proficient in Mandarin, with MoCA score greater than or equal to 26 points; Corrected normal vision and hearing
Exclusion criteria
Exclusion criteria: Known learning disabilities; Diagnosed as dementia; Diagnosed as a neurological or psychiatric disease; History of cancer drug treatment (excluding simple surgical treatment); Stroke in the past year; Mandarin language, hearing (with auxiliary equipment) or vision (with glasses) are not enough to complete the assessment task
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of cognitive impairment on postoperative days 1, 3, and 7 in two groups of patients;Comparison of intraoperative EEG burst suppression frequency and average frequency band power between two groups of patients;MoCA score;Vital signs; | — |
Secondary
| Measure | Time frame |
|---|---|
| General information on gender, age, ASA grading, height and body mass index of two groups of patients;Surgical conditions such as anesthesia time, surgical time, intraoperative blood loss, urine output, and infusion volume for two groups;Comparison of intraoperative dosages of sufentanil and remifentanil; | — |
Countries
zhangzhou
Contacts
Public ContactHuangNaqing
Zhangzhou Hospital
Outcome results
None listed