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A study on the effects of propofol and dexmedetomidine on sleep quality and hemodynamics in elderly patients undergoing painless colonoscopy under general anesthesia

A study on the effects of propofol and dexmedetomidine on sleep quality and hemodynamics in elderly patients undergoing painless colonoscopy under general anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400093430
Enrollment
Unknown
Registered
2024-12-04
Start date
2024-12-05
Completion date
Unknown
Last updated
2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sleep disorder

Interventions

Experimental group:Preoperatively, a loading dose of dexmedetomidine 1 µg/kg was infused over 10 min, followed by a infusion of 0.5 µg/kg/h during the operation, while propofol was administered intrav
Control group :Before surgery, an intravenous infusion of 1 µg/kg of normal saline was administered, followed by an intravenous injection of propofol 0.5 mg/kg/h to 2 mg/kg/h. During the operation, pr

Sponsors

The Third People's Hospital of Zigong
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Elderly patients who voluntarily underwent painless colonoscopy and were diagnosed by physicians with intractable sleep disorders as research subjects; 2. Age 60-90 years old (Chinese standard); 3. Those with an education level of primary school or above; 4. American Society of Anesthesiologists (ASA) grade I-III; 5. Patient-informed and voluntary participation in the study.

Exclusion criteria

Exclusion criteria: 1. Have cognitive dysfunction; 2. Have obstructive sleep apnea syndrome; 3. Body Mass Index (BMI) exceeding 28kg/m2 (Chinese obesity standard); 4. Adverse reactions to anesthetic drugs; 5. Patients who have any discomfort or actively withdraw during the experiment; 6. Patients who are unwilling to participate in this experiment, or who are unable to sign the informed consent form

Design outcomes

Primary

MeasureTime frame
PQSI;HAMD;

Countries

China

Contacts

Public ContactZhou Peng

The Third People's Hospital of Zigong

734187314@qq.com+86 135 5076 1755

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026