Diabetic retinopathy
Conditions
Interventions
Severe NPDR group :retinal laser treatment
PDR group :retinal laser treatment
Normal control group:None
Sponsors
School of Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, China
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Age 18-80 years old; (2) Have a history of diabetes; (3) fundus lesions were in line with the international standard of clinical DR Severity grading. Combined with fundus photography and fundus fluorescein angiography (FFA), DR Was clearly diagnosed, including non-proliferative diabetic retinopathy (NPDR) and proliferative diabetic retinopathy (PDR).
Exclusion criteria
Exclusion criteria: (1) dioptric interstitial ambiguity can not see the fundus; (2) iris adhesion can not dilate the pupil; (3) Those who have received laser photocoagulation or vitrectomy; (4) Patients with glaucoma, central retinal vein obstruction and other eye diseases; (5) People with a history of smoking and respiratory diseases; (6) Patients with a history of cardiovascular and heart disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| best corrected visual acuity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Retinal vascular functional indicators;Retinal vascular structural indicators; SD-OCT morphologic indexes;OCTA microvascular changes;Non-perfusion area in FFA;IOP(intraocular pressure); | — |
Countries
China
Contacts
Public ContactLeilei Lin
School of Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, China
Outcome results
None listed