Minimally invasive cardiac surgery
Conditions
Interventions
Remimazolam group:Anesthesia induction, remimazolam 0.2 mg.kg-1, sufentanil 0.6 µg.kg-1, rocuronium 1.0 mg.kg-1
anesthesia maintenance, injection of remimazolam 0.2~0.3 mg.kg-1.h-1 to maintain entropy index at 40~55
Propofol group:Anesthesia induction, propofol 0.1-0.2mg.kg-1, sufentanil 0.6 µg.kg-1, rocuronium 1.0 mg.kg-1
anesthesia maintenance, injection of propofol 0.3~0.5mg.kg-1.h-1 to maintain entropy index at 40~55
Sponsors
Zhejiang Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Age 18-65 years old, American Society of Anesthesiologists (ASA) grade II-III; (2) Patients undergoing elective mitral valve, aortic valve, and tricuspid valve surgery; (3) Patients with hypertrophic obstructive cardiomyopathy undergoing left ventricular outflow tract dredging.
Exclusion criteria
Exclusion criteria: (1) Patients with severe heart failure or hemodynamic instability before surgery; (2) Severe psychiatric illness or alcohol addiction in the past; (3) Patients with liver and kidney failure before surgery; (4) Patients with preoperative allergies to study drugs; (5) Patients with visual or language impairment before surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Extubation time;Length of stay in the hospital; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure;Heart rate;Length of stay in the ICU;Postoperative complications;Quality of Recovery-15 score;Transthoracic echocardiography;Urine output;The use of vasoactive agents; | — |
Countries
China
Contacts
Public ContactHuizi Liu
Zhejiang Provincial People's Hospital
Outcome results
None listed