valvular heart disease
Conditions
Interventions
PVB Group:Paravertebral nerve block was performed in bilateral T2-3 and T4-5 spaces under ultrasound guidance with 0.4% Ropivacaine and 14 mg compound betamethasone at each injection point followed by
ESPB Group:At first, 0.4% Ropivacaine and 14 mg compound betamethasone were injected into each injection site with 20 ml of drugs, then general anesthesia was performed.
TTMPB Group:Transthoracic muscle block was performed at bilateral T3-T4 intercostal space under ultrasound guidance. 0.4% ropivacaine and 14 mg compound betamethasone was injected into each injection
Sponsors
The Second Xiangya Hospital of Central South University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged over 18 years; 2. Elective cardiac valve surgery with cardiopulmonary bypass 3. ASA grade II-III; 4. New York Heart Association class II-III; 5. First Heart Surgery 6. Sign the informed consent form voluntarily.
Exclusion criteria
Exclusion criteria: 1. Contraindications to nerve block, including anatomical variations of the puncture site due to infection, tumor, or severe deformity, Coagulopathy, allergy to local anesthetics, etc. 2. History of chronic pain or opioid abuse 3. Mental Illness 4. Use of analgesics before surgery 5. Liver and kidney dysfunction 6. Others are not suitable for clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Amount of sufentanil used during operation;NRS scores at rest and cough at 24h and 48 h after operation;The Times of rescue analgesia within 24 h and 48 h after operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of mechanical ventilation;Length of stay in the ICU;Length of hospital stay; | — |
Countries
China
Contacts
Public ContactXu Junmei
The Second Xiangya Hospital of Central South University
Outcome results
None listed