Bronchus, lung, chest and other diseases
Conditions
Interventions
PS group:A combined sedation regimen of sufentanil and propofol
RA group:A combined sedation regimen of remimazolam and afentanil
MA group:A combined sedation regimen of midazolam and afentanil
Sponsors
Ningbo Beilun People’s Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.Age range 60-85 years; 2.ASA grade I - III; 3.No other serious systemic complications; 4.Conscious and able to cooperate with examination and treatment; 5.Patients gave informed consent and signed written informed consent;
Exclusion criteria
Exclusion criteria: 1.ASA grade greater than ?; 2.Patients with chronic alcohol addiction, long-term use of psychotropic drugs (such as sedants) and monoamine oxidase inhibitors; 3.Patients with severe liver dysfunction or abnormal renal function (such as preoperative dialysis); 4.Patients with cognitive impairment caused by mental and psychological disorders; 5.Patients with bronchial asthma, respiratory depression and myasthenia gravis and high sensitivity; 6.Patients with arrhythmia, preoperative left ventricular ejection fraction less than 30%, sick sinus syndrome, severe sinus bradycardia (< 50 beats/min), or atrioventricular block of degree II or above.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neuropsychological test;Sleep assessment (Mi Bracelet); | — |
Secondary
| Measure | Time frame |
|---|---|
| Perioperative hemodynamics;VAS choke score;Hypoxia incidence;Patient resuscitation time, i.e. the time required from the end of surgery until Aldrete sco;Patient satisfaction and Surgeon satisfaction;; | — |
Countries
China
Contacts
Public ContactYunfei Cao
Ningbo Beilun People’s Hospital
Outcome results
None listed