autoimmune hepatitis
Conditions
Interventions
Acute AIH:None
Acute-on-Chronic AIH:None
Chronic AIH:None
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
15 Years to 86 Years
Inclusion criteria
Inclusion criteria: 1) Diagnosed as "definitive AIH" according to the revised IAIHG score or simplified IAIHG score; 2) Have clear histological evidence and receive immunosuppressive therapy; 3) Acute AIH is characterized by meeting at least one of the following three criteria during the course of the disease: a) TB >=5mg /dL, b) ALT >=10×ULN, c) AST >=10xULN. At the same time, patients with acute AIH must meet the requirements of =26 weeks, b) liver histology S >=2, and c) radiographic cirrhosis. Patients with chronic AIH do not have the acute AIH symptoms described above.
Exclusion criteria
Exclusion criteria: 1) Other autoimmune liver diseases (primary biliary cholangitis/cirrhosis, primary sclerosing cholangitis, overlap syndrome); 2) With other chronic liver diseases and AIH is not the main cause, including viral hepatitis, alcoholic liver disease, metabolically related fatty liver disease, drug-induced liver injury, hereditary liver disease, etc.; 3) Lack of key diagnosis and treatment data (such as key tests or examinations, medication information, clinical events, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Full biochemical remission rate;Death;Relapse;liver transplantation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to obtain complete remission; | — |
Countries
China
Contacts
Public ContactYang Li
West China Hospital, Sichuan University
Outcome results
None listed