Cervical intraepithelial neoplasia
Conditions
Interventions
:None
CO2 laser treatment group alone
:CO2 laser
Human interferon alpha 2b vaginal effervescent tablet group
:Human interferon alpha 2b vaginal effervescent tablet
CO2 laser therapy plus human interferon a2b vaginal effervescent tablet group:CO2 laser and human interferon alpha 2b vaginal effervescent tablet
Sponsors
Anhui Women and Children Medical Center, China
Eligibility
Sex/Gender
Female
Age
30 Years to 55 Years
Inclusion criteria
Inclusion criteria: ? In accordance with the LSIL diagnostic criteria in the ninth edition of Obstetrics and Gynecology ? in patients with the same HR-HPV positive results for two cervical HPV tests more than six months apart ? the cervical squamo-column junction is completely visible under colposcopy; To be a type I transformation area ? must have TCT, HPV, HPV E6/E7 mRNA and pathological results ? voluntarily participate in the study and sign an informed consent letter
Exclusion criteria
Exclusion criteria: ? The colposcopy is not satisfied, or the cervix is II, III conversion area ? patients with acute genital tract inflammation and gonorrhea or non-gonococcal urethritis ? patients with unexplained vaginal bleeding ? patients with serious psycho-physical diseases are not suitable for this treatment ? patients with poor treatment compliance ? women in pregnancy or breastfeeding; ? People with HIV infection ? cervical cancer and high-grade cervical lesions ? are allergic to interferon preparations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Screening for high-risk human papillomavirus;Liquid-based thin layer cell detection;colposcopy;Human papillomavirus mRNA detection; | — |
Countries
China
Contacts
Public ContactYali Zhuang
Anhui Women and Children Medical Center
Outcome results
None listed