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Clinical observation of Qingying 2 in the treatment of Hashimoto thyroiditis and its effect on the polarization of immune cells

Clinical observation of Qingying 2 in the treatment of Hashimoto thyroiditis and its effect on the polarization of immune cells

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400093316
Enrollment
Unknown
Registered
2024-12-02
Start date
2025-01-01
Completion date
Unknown
Last updated
2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hashimoto thyroiditis

Interventions

control group:take selenious yeast tablets
experimental group:take Qingying 2 water decoction

Sponsors

Shanghai Municipal Hospital of Traditional Chinese Medicine Affiliated to Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Patients who meet the diagnostic criteria of Hashimoto's thyroiditis and the syndrome is liver depression and spleen deficiency; 2.20-65 years old, gender is not limited; 3.The measured values of T3, T4 and TSH are in the normal range; 4.Sign informed consent; 5.TPOAb > 300 IU/ml.

Exclusion criteria

Exclusion criteria: 1.Pregnant or lactating patients; 2.Anemia patients (male: hemoglobin <120g/L, female: hemoglobin <110g/L); 3.Patients with autoimmune hepatitis, chronic glomerulonephritis and other diseases were judged not suitable for participation in the trial by researchers; 4.Patients receiving drugs that may affect the conversion of thyroxine to triiodothyronine, or may affect thyroid autoimmune drug therapy and cannot be discontinued, including corticosteroids, amiodarone, propranolol, alpha interferon, etc.; 5.Osteoporosis; 6.Suffers from mental illness and is unable to stop taking related drugs.

Design outcomes

Primary

MeasureTime frame
Thyroid function related indicators;Cytokine expression;Number and proportion of Th17/Treg cells in peripheral blood;Number and proportion of Th1/Th2 cells in peripheral blood;

Secondary

MeasureTime frame
Thyroid gland function;Thyroid nodule;thyroid volume;TCM syndrome integral;

Countries

China

Contacts

Public ContactYi Chen

Shanghai Municipal Hospital of Traditional Chinese Medicine Affiliated to Shanghai University of Traditional Chinese Medicine

gogo1st@163.com+86 181 1607 0305

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026