Hashimoto thyroiditis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients who meet the diagnostic criteria of Hashimoto's thyroiditis and the syndrome is liver depression and spleen deficiency; 2.20-65 years old, gender is not limited; 3.The measured values of T3, T4 and TSH are in the normal range; 4.Sign informed consent; 5.TPOAb > 300 IU/ml.
Exclusion criteria
Exclusion criteria: 1.Pregnant or lactating patients; 2.Anemia patients (male: hemoglobin <120g/L, female: hemoglobin <110g/L); 3.Patients with autoimmune hepatitis, chronic glomerulonephritis and other diseases were judged not suitable for participation in the trial by researchers; 4.Patients receiving drugs that may affect the conversion of thyroxine to triiodothyronine, or may affect thyroid autoimmune drug therapy and cannot be discontinued, including corticosteroids, amiodarone, propranolol, alpha interferon, etc.; 5.Osteoporosis; 6.Suffers from mental illness and is unable to stop taking related drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Thyroid function related indicators;Cytokine expression;Number and proportion of Th17/Treg cells in peripheral blood;Number and proportion of Th1/Th2 cells in peripheral blood; | — |
Secondary
| Measure | Time frame |
|---|---|
| Thyroid gland function;Thyroid nodule;thyroid volume;TCM syndrome integral; | — |
Countries
China
Contacts
Shanghai Municipal Hospital of Traditional Chinese Medicine Affiliated to Shanghai University of Traditional Chinese Medicine