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A Clinical and Mechanistic Study on the Improvement of Balance in Stroke Patients through CIMT-Modified Tai Chi?

A Clinical and Mechanistic Study on the Improvement of Balance in Stroke Patients through CIMT-Modified Tai Chi?

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400093286
Enrollment
Unknown
Registered
2024-12-02
Start date
2024-12-02
Completion date
Unknown
Last updated
2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

and Tai Chi based on CIMT group:Tai Chi based on CIMT
Regular Tai Chi group:Regular Tai Chi Training

Sponsors

Shanghai Yangzhi rehabilitation hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.There is a clear diagnosis of stroke patients; 2.First onset, with a course of more than 3 months; 3.Fugl Meyer motor function score confirms motor dysfunction; 4.Age range: 18-70 years old, male or female not limited; 5.No cognitive or communication impairments, with a score of 23 or above on the Mini Mental State Examination (MMSE); 6.Capable of walking independently or with assistive devices for more than 10 meters;

Exclusion criteria

Exclusion criteria: 1.Patients with serious systemic diseases such as cardiovascular and pulmonary diseases who cannot tolerate rehabilitation treatment; 2.Diagnosed with mental illness, severe depression (with suicidal tendencies) or epilepsy, and individuals with a family history of mental illness or epilepsy; 3.Apart from death, suffering from other neurological disorders such as Parkinson's disease; 4.There are serious systemic diseases such as diabetes and uremia; 5.Bone and joint system injuries or diseases that affect balanced walking function, such as severe joint contractures, recent fractures of the trunk or lower limbs, osteoarthritis, osteoporosis, etc; 6.Suffering from any cause that leads to consciousness disorders; 7.According to safety guidelines, there are contraindications for TMS magnetic stimulation, such as the presence of metal foreign objects or other implanted electronic devices in the body; 8.Hearing or visual defects may affect assessment and treatment; 9.Drugs that alter the excitability of the cerebral cortex (such as antiepileptic drugs, sedative hypnotic drugs, etc.);

Design outcomes

Primary

MeasureTime frame
Near infrared brain functional imaging (fNIRS): real-time changes in cerebral blood flow oxygenated hemoglobin concentration during CIMT or regular tasks; The brain regions include PFC, SMA, and M1; C;

Secondary

MeasureTime frame
Assessment of Balance Activity Ability: Berg Balance Assessment; Timed standing and walking test; 10 minute walking test; Fugl Meyer Assessment Function (FMA);Assessment of limb spasticity: Modified Ashworth Score (MAS);Fall risk assessment: fall incidence rate, comprehensive activity specific fall risk assessment, activity specific balanced confidence scale;Activity independence assessment: Barthel index;EMG physiological testing: exploring the activation of muscles such as tibialis anterior and gastrocnemius under different exercise modes;Sports execution function: Purdue roof, dual task TUG;

Countries

China

Contacts

Public ContactZhang Jing

Shanghai Yangzhi rehabilitation hospital

zj_9748@163.com+86 188 1727 3616

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026