osteoarthritis
Conditions
Interventions
Research group:Ketoprofen gel patch combined with oral glucosamine sulfate
Control group:oral glucosamine sulfate
Sponsors
Affiliated Hospital of North Sichuan Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) The subjects voluntarily agree to participate in the study and sign a written informed consent; (2) Age 18-75 years old, male or female; (3) The patient was clinically diagnosed as unilateral osteoarthritis. According to Kellgren-Lawrence imaging grade, 0-? was early stage; Class ? ~ ? belongs to the middle stage; Grade ? belongs to the late stage, this study selected grade II to ?, VAS > 40mm; (4) No previous bleeding, asthma, severe cardiac, liver and renal insufficiency, non-steroidal drug allergy history;
Exclusion criteria
Exclusion criteria: (1) previous treatment that may affect the efficacy; (2) Patients with open wounds, scars or ulcers in the gel paste application area; (3) fracture, dislocation, etc.; Accompanied by tumors, cardiovascular and cerebrovascular diseases, blood diseases and other serious primary diseases, or accompanied by mental disorders and communication disorders can not determine the efficacy. Radiating pain or dysfunction caused by other diseases (visceral organ diseases, cardiovascular and cerebrovascular diseases); (4) Pregnant and lactating women or women of childbearing age who are trying to conceive; (5) Other situations in which the researcher considers it inappropriate to participate in this experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total effective rate;satisfaction; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS score;Western Ontario and McMaster University WOMAC ratings;Knee Lysholm score;Application comfort; | — |
Countries
china
Contacts
Public ContactQing Yufeng
Affiliated Hospital of North Sichuan Medical College
Outcome results
None listed