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Clinical observation on auricular vagus nerve stimulation for the treatment of intestinal obstruction after laparoscopic colorectal cancer surgery

Clinical observation on auricular vagus nerve stimulation for the treatment of intestinal obstruction after laparoscopic colorectal cancer surgery

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400093274
Enrollment
Unknown
Registered
2024-12-01
Start date
2024-12-01
Completion date
Unknown
Last updated
2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal cancer

Interventions

intervention group:The intervention was carried out 24 hours before surgery. Patients took a seated or semi-recumbent position, disinfected both ears with 75% alcohol cotton pads, and used Wang Bu Liu
Control group:The intervention was carried out 24 hours before surgery. The patients also took the sitting or semi-recumbent position, sterilised both ears with 75% alcohol cotton pads, used ear bean

Sponsors

Sixth Medical Centre, General Hospital of the People's Liberation Army, China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Patients between the age range of 50-70 years old, gender is not limited; (2) Diagnosed with primary colon cancer by total colonoscopy and pathological histological biopsy, and for the first time to perform laparotomy, no history of intestinal obstruction, no history of caesarean section; (3) Preoperative general condition is acceptable, body mass index 18Kg/m2<BMI = 31kg/m2, body mass index = weight (kg)/height (m2 ); (4) no application of medication to promote digestive function in the last 1 month; (5) intact skin of the ear, no allergy to the auricular acupoint patch, no serious flaking, redness, swelling and other skin abnormalities; (6) the patient can have normal communication, agree and sign the written informed consent form.

Exclusion criteria

Exclusion criteria: (1) patients with preoperative intestinal obstruction due to other causes; (2) patients suffering from serious underlying diseases such as heart, lung, brain, liver, kidney, psychiatric disorders, syncope, or history of epilepsy; (3) patients who need to be synchronised with other surgeries, or who have been switched from laparoscopic to open surgery intraoperatively; (4) patients who have intra-operative or postoperative complications requiring intensive care; (5) patients who need to undergo gastrointestinal fistulas postoperatively; (6) patients who have had auricular acupuncture treatment within 1 month prior to the surgery or the ear has damage or infection; (7) Those who are currently involved in other clinical trials, or those who have not yet completed 3 months from the end of their involvement in other clinical trials. (8) Patients with pacemaker application; (9) Patients with preoperative combined pain, those who are using central analgesic drugs, those who are addicted to or dependent on opioids, or those who have a history of alcoholism.

Design outcomes

Primary

MeasureTime frame
Time of first bowel movement;

Secondary

MeasureTime frame
First Anal Ventilation;Time of first fluid intake;Post-operative length of stay;Bloating conditions;Pain conditions;WBC;lymphocyte;gastrin;TNF-a;IL-1;IL-6;24-hour gastric fluid volume;

Countries

China

Contacts

Public ContactLi Chengxin

Department of Acupuncture and Moxibustion, Department of Traditional Chinese Medicine, Sixth Medical Center, PLA General Hospital

ericzerocustom@163.com+86 132 6345 9635

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026