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The Safety and Efficacy of Single-port Inflatable Mediastinoscopy Combined with Laparoscopic Radical Esophagectomy after Neoadjuvant Therapy

The Safety and Efficacy of Single-port Inflatable Mediastinoscopy Combined with Laparoscopic Radical Esophagectomy after Neoadjuvant Therapy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400093263
Enrollment
Unknown
Registered
2024-12-01
Start date
2023-12-12
Completion date
Unknown
Last updated
2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

There are no obvious symptoms or mild in early stage of esophageal carcinoma. The typical symptom is progressive dysphagia.

Interventions

Sponsors

Fifth Affiliated Hospital, Sun Yat-Sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.ESCC confirmed via digestive endoscopy combined with biopsy. 2.Underwent single-port inflatable mediastinoscopic radical esophagectomy (SIMRE). 3.Tumor center located in the thoracic esophagus. 4.Age between 18 and 80 years.

Exclusion criteria

Exclusion criteria: 1.Previous malignancy or chest radiotherapy before neoadjuvant chemoradiotherapy. 2.History of major thoracic or abdominal organ resection. 3.Serious organic diseases and dysfunction, such as acute cerebral infarction or severe sequelae, hypertension, diabetes, or arrhythmia. 4.Preoperative evaluation confirming distant metastasis.

Design outcomes

Primary

MeasureTime frame
LN disection;R0 resection;

Secondary

MeasureTime frame
Overall survival time;Disease-free survival time;Intraoperative blood loss;Surgery duration;Conversion;Postoperative Complications;

Countries

China

Contacts

Public ContactQingdong Cao

Fifth Affiliated Hospital, Sun Yat-Sen University

cqd8866@163.com+86 756 2528895

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026