oral lichen planus
Conditions
Interventions
T lymphocyte infiltration group:Cluster of Differentiation 3
T-B lymphocyte infiltration group:Cluster of Differentiation 3,Cluster of Differentiation 20
T-P lymphocyte infiltration group:Cluster of Differentiation 3,Cluster of Differentiation 38
T-B-P lymphocyte infiltration group:Cluster of Differentiation 3, Cluster of Differentiation 20, Cluster of Differentiation 38
Sponsors
Ninth People 's Hospital, Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Age over 18 years old ; 2.Patients with oral lichen planus diagnosed according to medical history, clinical manifestations and pathological examination and VAS score = 1 ; 3.Voluntary participation in this study, can participate in the review on time and can complete the whole research steps ; 4.Patients agreed to participate in the study and voluntarily signed informed consent, and can voluntarily provide personal medical history ;
Exclusion criteria
Exclusion criteria: 1.Patients with drug allergy or allergic constitution in this study ; 2.Patients with other confirmed oral mucosal diseases, or oral lichen planus classified as white stripe type asymptomatic, or with severe dysplasia or canceration ; 3.Patients with more serious systemic diseases and tumors ; 4.Participated in other clinical researchers in the past 3 months ; 5.Some drugs or silver amalgam fillings may cause moss-like reactions ; 6. pregnant and lactating women and those preparing for pregnancy during the study period ( based on information provided by the subjects ) ; 7. due to other chronic diseases, including after transplantation, the need for regular use of antibiotics, hormones, non-steroidal anti-inflammatory drugs, immunosuppressants, immune enhancers, cytotoxic drugs, cell cycle drugs or anticoagulant drugs on the oral mucosa of drugs or preparations ; 8.Severe tobacco and alcohol addicts ( drinking > 15 units per week, each unit refers to : 350ml beer or 150ml wine or 50ml spirits ; smoking > 25 cigarettes / day ) ; 9. Any mental illness, or other illness that may lead to a legally recognized limitation of capacity to act.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reticulation, Erythema, Ulceration (REU); | — |
Countries
China
Contacts
Public ContactJunjun Chen
Ninth People 's Hospital, Shanghai Jiaotong University School of Medicine
Outcome results
None listed