Severe acute pancreatitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Hospitalized patients who meet the western medical diagnostic criteria for SAP; 2. Chinese medicine diagnostic criteria for Visceral Solid-Heat Conjunction; 3. Aged 18-70 years old; 4. First diagnosis of AP, onset time not more than 48 hours; 5. Organ dysfunction (refer to the Improved Marshall Score > 2); 6. Blood calcium less than 2 mol/L (refer to the Ranson Score > 3);
Exclusion criteria
Exclusion criteria: 1. Patients with SAP caused by trauma, pregnancy, medication, tumor, or surgery; 2. Patients with severe heart, liver, kidney diseases or blood or immune system diseases; 3. Pregnant and lactating women; 4. Patients who are allergic to the medications involved in this study; 5. Patients with less than a course of treatment (7 d); 6. Patients who are unable to determine the efficacy of the treatment due to incomplete clinical data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood amylase;serum calcium;intra-abdoninal pressure;C-reactive protein;blood chemistry; | — |
Secondary
| Measure | Time frame |
|---|---|
| CGRP;IL-6;Traditional Chinese Medicine Syndrome Points; | — |
Countries
China
Contacts
Chengdu Pidu District People's Hospital