Pain
Conditions
Interventions
Control group:Anesthetic maintenance The anesthetic robot target controlled infusion of propofol, remifentanil to achieve sedative and analgesic effects
Research group:Anesthesia maintenance sedative and analgesic effects were achieved by target controlled infusion of propofol and esketamine with anesthetic robot
Sponsors
Huai'an Hospital Affiliated to Yangzhou University (The Fifth People's Hospital of Huai'an)
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: ? patients aged 18 ~ 65 years old for elective surgery. BMI 18-30 kg/m2. ? Patients with ASA Grade I to III ? operation time 1 to 5 hours, clear consciousness, and able to communicate normally.
Exclusion criteria
Exclusion criteria: Exclusion criteria: ? serious abnormal heart, brain, liver, kidney, lung function or diabetes, neuropathy; ? Patients who have taken antidepressants, sedatives, analgesics or beta-blockers in the last 6 months ? There is a serious risk of hypertension or increased intracranial pressure ? large children; ?BMI=30kg/m2; ?BMI=40kg/m2; ? Tracheotomy; ? Patients who use other methods of analgesia; Untreated or undertreated hyperthyroidism
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total amount of each anesthetic (propofol, ketamine, sufentanil, remifentanil) during the operation;Heart rate, blood pressure, WLI, BIS and PTI values of patients 5 min before anesthesia induction (T0), after induction (T1), intubation (T2), 1min after intubation (T3), and extubation (T4); | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative extubation time;VAS score after extubation;Analgesic remedies and dosage after extubation;Sleep condition back to ward on the day of operation; | — |
Countries
China
Contacts
Public ContactMeijuan Sun
Huai'an Hospital Affiliated to Yangzhou University (The Fifth People's Hospital of Huai'an)
Outcome results
None listed