osteoporosis, compression fracture
Conditions
Interventions
5. Parathyroid hormone testing
6. Detection of bone turnover markers.
Gold Standard:The T value detected by DXA is the gold standard, and a T value less than -2.5 is considered osteoporosis.
Index test:1. DXA inspection: BMD-T value, TBS value
2. X-ray and/or QCT examination
3. Blood routine, liver and kidney function
4. Serum calcium and vitamin D testing
Sponsors
Fifth Affiliated Hospital, Sun Yat-Sen University
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Suspects male patients with osteoporosis (aged over 50 years old) in clinical practice; 2.Female menopausal patients; 3.Regular pattern of renal failure in hemodialysis patients; 4.Patients meet the diagnostic criteria for diabetes; 5.Long term hormone therapy patients; 6.The image quality meets the standards and specifications;
Exclusion criteria
Exclusion criteria: 1.Lumbar compression fracture; 2.Serious hematological diseases such as multiple myeloma, leukemia, lymphoma; 3.Those who do not accept CT or X-ray examinations for other reasons; 4.Severe Malnutrition; 5.There are implants in the research area (lumbar spine or hip);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| T value of DXA;trabecular bone score(TBS) value;Accuracy;Sensitivity;Specificity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Probability of fracture occurrence;Probability of adverse events (such as poor therapeutic effect, fracture occurrence); | — |
Countries
China
Contacts
Public Contactyijie fang
Fifth Affiliated Hospital, Sun Yat-Sen University
Outcome results
None listed