[18F] AldoView PET/CT Imaging for Primary Aldosteronism Subtyping

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2400093214

Enrollment

Unknown

Registered

2024-11-29

Start date

2024-12-01

Completion date

Unknown

Last updated

2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary aldosteronism

Interventions

Gold Standard:Adrenal vein sampling, AVS

Index test:[18F]AldoView PET/CT

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1) Age> 18 years old; 2) Learn the whole process of the experiment, voluntarily participate in the study and sign the consent of informedness; 3) The diagnosis of Primary Aldosteronism is clear.

Exclusion criteria

Exclusion criteria: 1) Refuse to join the test, the patient or the close relative cannot understand or sign the consent of informed consent; 2) Patients with other common secondary hypertension, such as nephreal stenosis, substantial hypertension of renal, pheochromocytoma, cortisol hydodiamia, etc; 3) Patients with malignant tumors or severe heart, lung, kidney, and liver dysfunction; 4) Women during pregnancy or lactation, women with pregnancy plan during the trial period, and women who have high risk of pregnancy but have not taken any contraceptive measures; 5) Patients who have undergone adrenal surgery; 6) Patients with hormone -alternative treatment for adrenal cortical function; 7) Patients who have long -term use of glucocorticoids and cannot be disabled; 8)Suspected hypersensitivity to PET tracer; 9) Currently participating in other clinical studies; 10)Patients with incomplete data.

Design outcomes

Primary

Measure	Time frame
Percentage of patients achieving complete biochemical remission, partial biochemical remission;Percentage of patients achieving complete clinical remission, partial clinical remission;	—

Secondary

Measure	Time frame
Percentage of patients achieving complete biochemical remission, partial biochemical remission;Percentage of patients achieving complete clinical remission, partial clinical remission;Number of reductions in hypertension medications;Predictive accuracy;Area Under Curve ( AUC );Sensitivity, SE;Specificity, SP;Youden index;	—

Countries

China

Contacts

Public ContactXianghang Luo

Xiangya Hospital of Central South University

xianghangluo@hotmail.com+86 139 7589 9012

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026