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A clinical study of transtendon puncture combined with iTBS mode transcranial magnetic stimulation on increased muscle tone in the hands of patients with stroke spasticity

A clinical study of transtendon puncture combined with iTBS mode transcranial magnetic stimulation on increased muscle tone in the hands of patients with stroke spasticity

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400093206
Enrollment
Unknown
Registered
2024-11-29
Start date
2024-12-01
Completion date
Unknown
Last updated
2024-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Platoon group:Addition of transtendon puncture therapy to conventional rehabilitation and drug therapy
iTBS group:Stimulation of the M1 area of the cerebral cortex on the affected side is supplemented with iTBS in addition to routine rehabilitation and medical therapy
Joint group:iTBS was treated in addition to conventional rehabilitation and medication on the same regimen as in the iTBS group. Then acupuncture treatment was carried out, and the protocol was the sa

Sponsors

The Second Affiliated Hospital of Anhui Medical University, Economic Development Zone, Hefei City, Anhui Province
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. The diagnostic criteria meet the "Key Points for the Diagnosis of Major Cerebrovascular Diseases in China 2019" published by the Neurology Branch of the Chinese Medical Association in 2019; The diagnostic criteria for upper limb spasticity were formulated with reference to the key points of spasticity diagnosis in the Clinical Diagnosis and Treatment Guidelines ·Physical Medicine and Rehabilitation" of the Chinese Medical Association. 2. First onset and duration of less than 6 months; 3. Age 35~75 years old; 4. MMSE score=20 points; 5. Brunnstrom stage III-IV. of the affected hand; 6. Improved Ashworth Grade 1-3; 7. Patients or family members voluntarily participate in the study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Other intracranial diseases in the past; 2. Those with recent progressive aggravation of their condition; 3. Those with absolute contraindications to transcranial magnetism; 4. Severe aphasia, audio-visual impairment, illiteracy, etc.; 5. Patients who have recently continued to take sedatives and muscle relaxants; 6. Patients with other serious heart, lung, brain and kidney diseases; 7. Those who are unable to cooperate and cannot tolerate it; 8. Those who participate in other clinical experiments at the same time.

Design outcomes

Secondary

MeasureTime frame
Upper extremity portion of the mini-Fugl-Meyer rating scale;Improved Ashworth classification;Modified Barthel index;

Primary

MeasureTime frame
Motor evoked potentials;Oxyhemoglobin in the cerebral cortex;

Countries

China

Contacts

Public ContactWei Xinchun

The Second Affiliated Hospital of Anhui Medical University, Economic Development Zone, Hefei City, Anhui Province

BengbuLili@163.com+86 187 1247 8329

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026