Thrombotic diseases
Conditions
Interventions
Sulodexide injection group:None
Sponsors
Renmin Hospital of Wuhan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >=18 years old 2. Patients hospitalized for =5 days 3. Sulodexide injection or low molecular weight liver should be used to prevent venous thromboembolism during hospitalization 4. At least 1 dose of Sulodexide injection or 1 dose of low molecular weight heparin during hospitalization 5. Continued hospitalization for more than 2 days after initial treatment with Sulodexide injection or low molecular weight heparin
Exclusion criteria
Exclusion criteria: 1.No routine blood tests, liver function, kidney function, and coagulation function were performed within 7 days prior to the first application of Sulodexide injection (intramuscular or intravenous) or low molecular weight heparin 2.No routine blood test or coagulation function test was performed after the first application of Sulodexide injection (intramuscular or intravenous) or low molecular weight heparin was used 3.During hospitalization, a definite diagnosis of acute coronary syndrome (acute myocardial infarction, unstable angina pectoris) 4.A clear diagnosis of acute stroke (ischemic or hemorrhagic stroke) during hospitalization 5.Patients hospitalized due to heavy bleeding or active bleeding events (including bleeding gums, blood in stool, blood in urine, etc.) 6.INR>=3 times the upper limit of normal within 1 week prior to Sulodexide injection or low molecular weight heparin 7.aPTT>=3 times the upper limit of normal within 1 week prior to Sulodexide injection or low molecular weight heparin 8.Platelet count <10×109/L within 1 week before Sulodexide injection or low molecular weight heparin 9.During this hospitalization, a diagnosis of deep venous thrombosis or pulmonary embolism of the lower extremity was made prior to Sulodexide injection or low molecular weight heparin
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood routine examination;Coagulation function;Venous thrombus; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood biochemistry; | — |
Countries
China
Contacts
Public ContactJunfen Zeng
Renmin Hospital of Wuhan University
Outcome results
None listed