acute mountain sickness
Conditions
Sponsors
Second Affiliated Hospital of Army Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria for cohort A (1) The population of people aged 18-30 who plan to rush from plain to plateau 3000 meters, with a peaceful constitution; (2) Previous physical health without a history of serious digestive diseases; (3) No history of other diseases with heart or respiratory; (4) Capable of self-care and comprehension of language; (5) Willing to participate in this study and sign an informed consent. Inclusion criteria for cohort B (1) Work and reside in Tibet (altitude>3000m) for 5-10 years, stay in Tibet at least for 9 months per year, aged 18-30 years old; (2) No history of severe gastrointestinal diseases; (3) No history of other diseases with heart or respiratory; (4) Capable of self-care and comprehension of language; (5) Willing to participate in this study and sign an informed consent.
Exclusion criteria
Exclusion criteria: (1) Individuals who have previously experienced severe acute mountain sickness, other illnesses such as chronic headache, dizziness, chronic diarrhea, abdominal pain, and severe sleep disorders; (2) Long term take therapeutic drugs or vitamin supplements; (3) Have used antibiotics in the past month; (4) Have taken probiotics orally in the past month for 3 days or more; (5) I have taken proton pump and acid suppressing digestive system drugs orally in the past month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Constitution in Chinese Medicine Questionnaire;Pittsburgh Sleep Quality Index;Gastrointestinal Symptom Rating Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| 16Sr DNA sequencing;metagenomics;fecal metabolomics;hematometabolomics;routine blood test;liver and kidney function; | — |
Countries
China
Contacts
Public ContactJing Cai
Second Affiliated Hospital of Army Medical University
Outcome results
None listed