Depression
Conditions
Interventions
Study Group:Pharmacotherapy + Eustimulation
Control group:Pharmacotherapy + pseudo-stimulation
Sponsors
Hangzhou Seventh People's Hospital
Eligibility
Sex/Gender
All
Age
12 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1)The diagnostic criteria for patients with depression meet the diagnostic criteria of the United States Diagnostic and Statistical Manual of Mental Disorders (DSM-5). 2)Hamilton Depression Rating Scale score (HAMD-24) > 24 points. 3)Meet DSM-5 diagnostic criteria for non-suicidal self-injury (5 self-injuries in the past 12 months= and 1 self-injury >= in the past 2 weeks. 4)Age 12-18 years old (including 12 years old, 18 years old), gender is not limited. 5)Patient and guardian give informed consent and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Informed consent of the patient and guardian and signing of the informed consent form. 2) Severe cerebral organic diseases, such as epilepsy, stroke, traumatic brain injury, etc. 3) Those with metal implants, such as pacemakers, artificial valves, and other TMS contraindications. 4) Received MECT within the past 12 months or rTMS in the past 3 months. 5) History of suicide attempt or suicide attempt in the past 24 months. 6) Left hand.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cortisol;Hamilton Depression Scale,HAMD;Beck Depression Inventory; | — |
Secondary
| Measure | Time frame |
|---|---|
| The Ottawa Self-Injury Inventory;Functional Assessment of Self-Mutilation,FASM; | — |
Countries
China
Contacts
Public ContactZhaowei Jiang
Hangzhou Seventh People's Hospital
Outcome results
None listed